Oxygen chambers, these "high-pressure vessels" integrating barometric science and life medicine, are transitioning from hospital intensive care units to 全民健身场 (fitness arenas). This paper analyzes the differentiated principles of hyperbaric oxygen therapy (HBOT) chambers and hypobaric chambers (simulating high-altitude environments), combined with the clinical practices of the large oxygen chamber cluster at Guiyang Guanshan Hospital and cutting-edge applications in sports rehabilitation, to reveal their core values in emergency medicine, tissue repair, and sub-health intervention. Data shows the global oxygen chamber market grows at an annual rate exceeding 12%, with China having built the largest single hyperbaric oxygen therapy center in the Asia-Pacific. The article delves into how oxygen chambers break through the hemoglobin oxygen-carrying limit, achieving a 30-fold increase in plasma dissolved oxygen under 2.5x atmospheric pressure, and how hypobaric environments activate the natural mechanism of erythropoietin (EPO), presenting readers with a 160-year history of baromedical evolution.